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High Purity Ubenimex 58970-76-6

XI’AN TIANXINGJIAN PHARMCHEM ENTERPRISES CO.,LTD

High Purity Ubenimex 58970-76-6

Certification : Haccp

Place of Origin : China

MOQ : 1kg

Price : ask us

Payment Terms : T/T, L/C

Delivery Time : 5-8 days

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What's ubenimex?

Ubimex is a competitive, reversible protease inhibitor. It is effective against arginylaminopeptidase (aminopeptidase B), leukotriene A4 hydrolase (a zinc metalloprotease showing epoxide hydrolase and aminopeptidase activity), alanylaminopeptidase (aminopeptidase M) / N), Leucyl / cysteine aminopeptidase (oxytocin / vasopressin enzyme) (leukotriene D4 hydrolase) has an inhibitory effect.
It is being studied for the treatment of acute myeloid leukemia
CAS NO.
58970-76-6
MF
C16H24N2O4
Appearance
White crystal powder
Purity
99%
Shelf life
2 years
Storage
Dry and cool place

Function:

1).Ubenimex is a dipeptide compound isolated from the culture solution of Streptomyces ofivorecticuli, which can competitively inhibit aminopeptidase N / CD13 and leucine peptidase.

2).Enhance the function of T cells, enhance the killing activity of NK cells, and increase the synthesis of colony stimulating factors to stimulate the regeneration and differentiation of bone marrow cells.
3).Ubenimex can interfere with tumor cell metabolism, inhibit tumor cell proliferation, cause tumor cell apoptosis, and activate human cell immune function, stimulate the production and secretion of cytokines, and promote the production and proliferation ofanti-tumor effector cells.
Application:
1).Ubenimex can enhance immune function, used for adjuvant therapy of anti-cancer chemotherapy, radiotherapy, senile immune function defects, etc.
2).It can be used in combination with chemotherapy, radiotherapy and combination therapy for leukemia, multiple myeloma, myelodysplastic syndrome, hematopoietic stem cell transplantation, and other solid tumor patients.

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